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Scientist/Senior Scientist - Automation Development

Walpole, Massachusetts
Job Type
23 Sep 2022

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Job Description About the role:

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.

Join Takeda as a Scientist/Sr Scientist - Automation Development where you will be responsible for designing and executing laboratory experiments to support assay development on an automation platform and phase appropriate qualification of high throughput methods. The focus will be on the development and automation of methods to support process development, high-throughput screening and non-GMP release and stability. As part of the Analytical Development team, you will report to Lead Analytical Development.

Must demonstrate expertise with liquid handling technologies (Tecan Fluent, Hamilton Vantage) and Excel spreadsheets and Macros to generate Worklists. Familiarity with the principles of ELISAs, qPCR, activity assays, binding assays and UPLC/HPLC Platforms are desired. Proficiency with programming languages, developing/modifying API's, liquid handler liquid class generation and hardware troubleshooting, 3D printing, wearable technology and robotics process automation are highly desired . Willingness and enthusiasm to work in an exciting and challenging field is a must. The ability to work independently and/or within a team environment is essential. An innovative mindset is necessary to both solve problems and develop, lead, and manage initiatives to bring greater efficiency to the department. The candidate must be able to effectively communicate cross-functionally with internal and external partners (CRO/CMO's).

How you will contribute:
  • Automation of methods and evaluation of automatable platform methods and technologies to support process development, high-throughput screening and non-GMP release and stability (30 %)

  • Design and participate in phase appropriate qualification and transfer of automated methods (10 %)

  • Author and review technical documents such as protocols, SOPs, and reports. Training of personnel for purposes of broadening the Advanced Analytical Technologies Toolkit. (10 %)

  • Manage outsourced activities pertaining to the evaluation of automation platforms (15 %)

  • Project/Analytical Sub-team Representation (5 %)

  • Present data/results in group and department meetings (10 %)

  • Seek out and evaluate novel technologies (20 %)

Minimum Requirements/Qualifications:
  • Ph.D. in Biology, Chemistry, Biochemistry, Bioengineering or related discipline with a minimum of 0 years of industry experience (3 years for Sr Scientist)

  • MS in Biology, Chemistry, Biochemistry, Bioengineering or related discipline with a minimum of 6 years relevant industry experience (9 years for Sr Scientist)

  • BS in Biology, Chemistry, Biochemistry, Bioengineering or related discipline with a minimum of 8 years relevant industry experience (11 years for Sr Scientist)

  • Computer science background highly desirable

  • Working knowledge of common analytical platforms not limited to: ELISA, qPCR, enzyme activity assays, binding assays, and HPLC/UPLC platforms

Knowledge, Skills, and Ability:
  • Develop complex strategic approaches and methodologies within expertise with an understanding of how to weigh and assess technical risks. Leverage understanding of project timelines and big picture (eg, impact on resources across functions in Pharm Sci).

  • Author and/or review technology transfer documentation

  • Identify and plan broader technical objectives both project and scientific related and executes plans department wide independently or with input from management. Initiates the development of operational processes to facilitate these objectives for future projects, either independently or in consultation with manager.

  • Coordinating cross-functional team and providing resolutions to scientific/technical challenges. Expected to fully represent their functional area to a PS sub-team or other cross functional team.

  • Has sound knowledge of cGMP practices

  • Expertise in multiple technologies to support automated assay development

  • May represent Takeda in relationships with universities and industrial consortia

  • May have accountability for performance and results of team (direct reports or project/team members that are internal or external

  • May require approximately 5% travel

What Takeda can offer you:
  • 401(k) with company match and Annual Retirement Contribution Plan

  • Tuition reimbursement

  • Company match of charitable contributions

  • Health & Wellness programs including onsite flu shots and health screenings

  • Generous time off for vacation and the option to purchase additional vacation days

  • Community Outreach Programs

More about us:

At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.

Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

In accordance with the CO Equal Pay Act, Colorado Applicants Are Not Permitted to Apply.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations Lexington, MA Worker Type Employee Worker Sub-Type Regular Time Type Full time
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  • Job Reference: 719466980-2
  • Date Posted: 23 September 2022
  • Recruiter: Takeda Pharmaceutical
  • Location: Walpole, Massachusetts
  • Salary: On Application
  • Sector: Science & Technology
  • Job Type: Permanent